Deep dives into bioinformatics, computational biology, and data science. Written by researchers, for researchers.
An accessible introduction to bioinformatics, covering what it is, why it matters, and how biology and computer science converge to solve modern scientific challenges.
A practical walkthrough of the RNA-Seq analysis pipeline, from quality control and alignment to differential gene expression using DESeq2.
How DeepMind's AlphaFold transformed structural biology, what it means for drug discovery, and how you can use it in your own research.
Step-by-step guide to performing molecular docking simulations using AutoDock Vina, from ligand preparation to binding affinity analysis.
An introduction to single-cell RNA sequencing, how it differs from bulk RNA-Seq, and the computational tools used to analyze single-cell data.
How metagenomic sequencing reveals the hidden world of microbial ecosystems and the bioinformatics tools used to analyze them.
How machine learning is accelerating drug discovery, from molecular property prediction to generative chemistry and clinical trial optimization.
The computational side of CRISPR genome editing — from guide RNA design to off-target prediction and editing outcome analysis.